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Updated: May 5, 2026

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
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コカインに曝露した後のCX3CL1/CX3CR1軸の性別特異的調節障害:潜在的な禁欲のバイオマーカルのトランスレーション証拠

Oscar Porras-Perales1, Laura Sánchez-Marín2, Dina Medina-Vera3

  • 1Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain; Área del Corazón, Hospital Universitario Virgen de la Victoria, Málaga, Spain; Facultad de Psicología, Universidad de Málaga, Málaga, Spain.

Progress in neuro-psychopharmacology & biological psychiatry
|September 2, 2025
PubMed
まとめ

コカインはマウスとメスのネズミの脳炎症経路を異なる形で変化させ,CX3CL1/CX3CR1軸に影響を与えます. プラズマのCX3CL1レベルは,特に男性の禁酒期間と相関しており,コカイン使用障害の潜在的な性別のバイオマーカーを示唆しています.

キーワード:
禁欲 禁欲 禁欲バイオマーカーコカインフラクタルキン性二型化トランスレーション

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