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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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アトラル酸は,NRF2経路の活性化によりフェロプトーシスを抑制することで,慢性的な間欠性低酸素誘発性肺損傷を弱める

Jingjing Chen1, Lu Zhou2, Mengxin Li1

  • 1Jiangsu Marine Pharmaceutical Resources Development Engineering Research Center, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China.

Toxicology and applied pharmacology
|September 2, 2025
PubMed
まとめ

アトラリック酸 (AA) は慢性断続性低酸素 (CIH) に起因する肺損傷から保護します. AAはNrf2経路を活性化することで炎症と酸化ストレスを軽減し,阻害性睡眠呼吸不全症候群 (OSAHS) のような状態の治療の可能性を提供します.

キーワード:
アトラル酸慢性的な中断性低酸素フェロプトーシス酸化ストレス

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