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Updated: Sep 9, 2025

Microsurgical Skills of Establishing Permanent Jugular Vein Cannulation in Rats for Serial Blood Sampling of Orally Administered Drug
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Microsurgical Skills of Establishing Permanent Jugular Vein Cannulation in Rats for Serial Blood Sampling of Orally Administered Drug

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ネズミにおけるクロピドグレル-フェルル酸コンジュガートの薬理動力学とシステム前生物変換

Rong Shen1, Huan Yang1, Yu Song2

  • 1Research Center for Drug Metabolism, School of Life Science, Jilin University, Changchun, China.

Journal of pharmaceutical sciences
|September 2, 2025
PubMed
まとめ

クロピドグレルの新しい派生物であるDclop- FAは,薬剤の投与を強化し,生物変換を改善することにより,その変異性を減少させます. この新しいアプローチは,クロピドグレル耐性を克服し,患者の治療結果を改善するための有望な戦略です.

キーワード:
Dclop-FA についてクロピドグレル耐性エステラゼ薬理学システム前水解

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