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Updated: Sep 9, 2025

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
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T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

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次世代配列化によって特定されたB細胞受容体レパートリーは,HIV感染者における不完全な免疫再構成と関連したシグネチャーを示した

Yu-Jie Zhan1, Wei Liu1, Bu-Yi Wang1

  • 1Department of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.

Clinical immunology (Orlando, Fla.)
|September 2, 2025
PubMed
まとめ

抗レトロウイルス治療 (ART) を受けるHIV患者におけるB細胞受容体 (BCR) は,免疫再構成に影響を与える可能性があります. 非反応者の特定のBCR特性は,HIVのgp41タンパク質を標的とする抗体との関連を示唆する.

キーワード:
6ヘリックスバンドルをターゲットにABSB細胞受容体レパートリーHIV ウイルス重鎖補完決定領域 3免疫不反応者次世代シーケンシング

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