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Updated: Sep 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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シナミック酸骨格を含むインダノンの誘導体の設計,合成,および抗炎症作用に関する研究

Yu Zou1, Yangyang Ren1, Yuhui Liu2

  • 1Institute of Pharmaceutical Process, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan 430065, China.

Fitoterapia
|September 2, 2025
PubMed
まとめ

新型1-インダノンの誘導体は,活性酸素種 (ROS) と炎症マーカーを阻害することで強力な抗炎症効果を示しています. 化合物6aと6oは,炎症調節における治療開発の有意な可能性を示しています.

キーワード:
1-インダノン誘導体抗炎症薬シナミック酸自然産物のデリバティブ

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