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Updated: May 10, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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乳がん細胞にメトトレキサートとクルクミンを同時に投与するためのレドックス誘発ヒアルロン酸ポリマーソーム

Sourena Ahrar1, Fatemeh Bagheri2, Fariba Ganji1

  • 1Department of Biomedical Engineering, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.

International journal of biological macromolecules
|September 2, 2025
PubMed
まとめ

カルキュミンとメトトレキサートで共負荷されたレドックス感受性ポリマー群は,CD44過剰発現する乳がん細胞を標的とする. この二重薬剤投与システムは,抗がん効果を高め,癌細胞の生存能力を低下させ,著しいアポトーシスを誘導します.

キーワード:
二重薬物投与ヒアルロン酸レドックス反応性ポリマーソーム

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