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Updated: Sep 9, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

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アミノ酸に依存するTSC2のリソソームPP2Aによる脱リン化がmTORC1信号伝達を調節する

Takanori Nakamura1,2,3,4, Shigeyuki Nada5, Masaki Matsumoto6

  • 1Division of Cell Signaling and Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan nakamura.takanori.cb@ehime-u.ac.jp.

Life science alliance
|September 2, 2025
PubMed
まとめ

この研究は,ラパミシン複合体1 (mTORC1) の哺乳類の標的経路をモデル化し,アミノ酸と成長因子の相互作用を明らかにしています. mTORC1の完全な活性化には 両方の信号が必要で これは代謝疾患の理解に不可欠です

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