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Updated: Sep 9, 2025

Assessment of Kidney Function in Mouse Models of Glomerular Disease
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Assessment of Kidney Function in Mouse Models of Glomerular Disease

Published on: June 30, 2018

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セルピンE2欠乏症は,血管新生と炎症反応の調節不良により,糖尿病性腎不全における球損傷を悪化させる

Leila Idir1, Junjie Yu1, Philippe Bonnin1,2

  • 1LVTS, INSERM U1148, Université Paris Cité and Université Sorbonne Paris Nord, F-75018 Paris.

American journal of physiology. Renal physiology
|September 2, 2025
PubMed
まとめ

SerpinE2欠乏症は,マウスにおける糖尿病性腎不全 (DN) を悪化させ,球球損傷,炎症,腎機能障害を増加させます. これは,SerpinE2がDNの進行において保護的役割を果たしていることを示唆している.

キーワード:
血管新生糖尿病性腎臓病サーピン

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