FGF21とGDF15は,熱性脂肪細胞にOPA1が欠けているマウスの全身代謝ホメオスタシスを調節するために相乗的に作用する

Joshua Peterson1, Jayashree Jena1, Ayushi Sood1

  • 1Fraternal Order of Eagles Diabetes Research Center and Department of Internal Medicine, Division of Endocrinology and Metabolism, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

PubMed
まとめ

茶色脂肪に光学縮1 (OPA1) が欠けているマウスは,部分的に線維細胞成長因子21 (FGF21) と成長分化因子15 (GDF15) によって肥満に抵抗する. これらの要因は共に作用し 代謝の健康を維持します

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