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Updated: Sep 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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炭素と窒素の原子交換は,薬のようなインドルからベンジミダゾールへの直接アクセスを可能にします

Ann-Sophie K Paschke1, Yannick Brägger1, Bence B Botlik1

  • 1Laboratorium für Organische Chemie, ETH Zürich, Zurich, Switzerland.

Nature chemistry
|September 2, 2025
PubMed
まとめ

この研究は,炭素を窒素に置き換えてインドルをベンジミダゾールに変換する単一の原子交換のための新しい方法を導入しています. この進歩は,医薬品と農業化学の研究のための新しいツールを提供します.

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