ヒトパピローマウイルスに関連するシンタキシン11は,PI3K/AKTシグナル伝達を通じて乳がん細胞アポトーシスを誘発するために腫瘍関連マクロファージを再プログラムする

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Updated: Sep 9, 2025

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes
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Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes

Published on: August 24, 2021

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Chuan Hu1,2, Tingting Hu3,4,5, Jian Wen6,7

  • 1Department of Interventional Therapy, Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, China.

Molecular medicine (Cambridge, Mass.)
|September 2, 2025
PubMed
まとめ

ヒトパピローマウイルス (HPV) は乳がん (BC) の進行に影響します. この研究は,新規のHPV関連遺伝子シグネチャを特定し,マクロファージの極化による抗腫瘍免疫の促進におけるSTX11の役割を明らかにし,BC免疫療法の可能性を提示しています.

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