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Updated: Sep 9, 2025

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KRAS変異は,ZNF24/SLC7A5/PD-L1軸経由で肺腺がんの免疫脱出を促進する

Leilei Li1,2, Qiang Feng2, Ya Jiang2

  • 1Graduate School, Kunming Medical University, Kunming, Yunnan, 650500, People's Republic of China.

BMC cancer
|September 2, 2025
PubMed
まとめ

KRAS変異はZNF24/SLC7A5/PD-L1経路経由で肺腺がんの免疫脱出を促す. ZNF24をダプトマイシンとPD- L1阻害で標的化すると,これらの患者の抗腫瘍免疫が強化される可能性があります.

キーワード:
免疫脱出KRAS変異肺腺がんPD-L1 についてZNF24 について

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