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Updated: Apr 12, 2026

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

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腸直腸腺がん細胞系におけるアポトーシスの誘導におけるバチルス・コアグルランス・ハンマーのプロバイオティクスの可能性 in vitro

Maryam Mashhoori Vayghan1, Parvaneh Saffarian1, Maryam Tajabadi Ebrahimi2

  • 1Department of Biology, SR.C., Islamic Azad University, Tehran, Iran.

BMC complementary medicine and therapies
|September 2, 2025
PubMed
まとめ

プロバイオティクスのバチルス・コアグルランス・ハマー系は,結腸癌細胞のアポトーシスを誘発することで,抗癌的可能性を示しています. これらの発見は,大腸がん (CRC) の予防と治療のための新しい治療アプローチを示唆しています.

キーワード:
バチルス・コアグルランス・ハンマーアポトーシス大腸がん細胞細胞外膀フローサイトメトリープロバイオティクス

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Phagocytosis of Apoptotic Cells

Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
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Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
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