インパクト・アファント:ノボ・ノルディスク財団の資金調達の新しい形式
Gert Vilhelm Balling1, Henrik Barslund Fosse2, Katrine Zander Iversen2
1Impact Management, Novo Nordisk Foundation, Hellerup, Denmark. gvb@novo.dk.
Health research policy and systems
|September 2, 2025
まとめ
医療研究の資金提供者は 今や 潜在的影響を前向きに分析して 成果を向上させることができます この革新的なアプローチは,確立されたガイドラインに沿って,プロジェクトの開始から評価まで,インパクトマネジメントを導くものです.
科学分野:
- 健康研究への資金提供
- 研究影響評価
- 慈善財団
背景:
- Payback Frameworkのような遡及的枠組みは,健康研究の影響を評価するために一般的です.
- 国際研究影響評価学校 (ISRIA) の声明は,2018年にこの経験の多くをまとめました.
- 管理や成果を向上させるために 潜在的影響を分析する資金提供者はほとんどいない.
研究 の 目的:
- ノボ・ノルディスク財団が開発した先駆的な将来的な影響分析と管理方法について説明します.
- 研究資金にインパクトアセスメントを統合するための5段階の連続性を概説する.
- 研究効果を高めるための影響管理戦略を策定する.
主な方法:
- 物語の準備,論理モデルの構築,早期の潜在的な影響評価,指標付きのデータモデルの実装,モニタリング/インパクト製品の作成.
- 国際研究影響評価学校 (ISRIA) のガイドラインとアプローチを整合させる.
- 予測的な影響分析を統合し,積極的な影響管理を図る.
主要な成果:
- ノボ・ノルディスク財団は,前向きな分析アプローチで影響評価を革新しています.
- 5段階のプロセスは,研究イニシアチブを初期からデータ評価と管理まで導くものです.
- このアプローチは,情報に基づいた管理を通じて達成された影響レベルを高めます.
結論:
- ノボ・ノルディスク財団の展望的なアプローチは,研究影響評価における重要な革新です.
- 特に包括的な利害関係者の関与を拡大するには,さらなる進歩が必要です.
- この方法は,他の資金提供者が積極的な管理を通じて研究効果を高めるためのモデルを提供します.
関連する概念動画
01:28Preclinical Development: Overview
4.8K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
4.8K
01:16Clinical Trials
7.8K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
7.8K
01:02Prescription, Nonprescription and Orphan Drugs
842
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
842
01:11Clinical Trials: Overview
3.4K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.4K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
174
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
174
01:26Drug Discovery: Overview
8.7K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
8.7K