APOE遺伝子型が老齢マウスの脳代謝に及ぼす影響 - APOE2遺伝子型におけるレジリエンスメカニズムにおけるミトコンドリアエネルギーの役割

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...