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Updated: Sep 9, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

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STINGと非ネクロプトティックMLKL媒介のメカニズムは,デンドリティック細胞の成熟と癌細胞の破壊を改善する

Trine S Jensen1, Marlene F Laursen1, Lea Schort1

  • 1Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aarhus, Denmark.

European journal of immunology
|September 3, 2025
PubMed
まとめ

カスパース抑制は,細胞死なしにSTING経路経由で dendritic cell (DC) の成熟を促進する. このDC成熟は癌細胞の死滅を引き起こし 新しい免疫療法標的を明らかにします

キーワード:
MLKLスティングカスパスデンドリット細胞ネクロプトーシス

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