ダフネチンは,JAK2/STAT3信号経路を通じて,腎臓の炎症,酸化ストレス,アポトーシスを軽減する

Zhuo Zhang1, Pan Hu1, Qingye Li1

  • 1Department of Emergency, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.

PubMed
まとめ

ダフネチン (DAP) は,炎症,酸化ストレス,細胞死亡を減少させることで,敗血症による急性腎臓損傷 (AKI) に対して保護します. JAK2/ STAT3シグナル伝達経路を阻害することで作用し,この重大な状態に対する潜在的な治療戦略を提供します.

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