関連する実験動画

Updated: Sep 9, 2025

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat
12:41

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Published on: August 28, 2021

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デクスメドトミジンの使用と重症外科患者の妄想との関連: 遡及的なコホート研究

Jiwoo Suh1, KyeongTeak Oh2, JiYeon Choi3,4

  • 1Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

Korean journal of anesthesiology
|September 3, 2025
PubMed
まとめ

手術用ICUでのデクスメドトミジンの使用は,妄想の発生率の増加とICU滞在の延長に関連していた. これは 妄想を予防するために 普段使うのではなく 個別的な鎮静療法が必要であることを示唆しています

キーワード:
集中治療デリリウムデックスメデトミジン催眠薬集中治療室リスク要因鎮静剤

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
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