家庭での医療を受ける高齢者に対する不適切な薬剤
Yukari Hattori1, Taro Kojima2, Hironobu Hamaya3
1Department of Geriatric Medicine, The University of Tokyo, Tokyo, Japan.
Annals of geriatric medicine and research
|September 3, 2025
まとめ
潜在的に不適切な薬 (PIMs) は,家庭医療を受ける介護に依存した高齢者の間で一般的です. 特に障害のある人にとって 病院入院のリスクを減らすには 薬を慎重に検討することが重要です
科学分野:
- ゲロントロジー
- 薬理学について
- 公衆衛生
背景:
- 家庭医療は高齢者にとって不可欠です
- 潜在的に不適切な薬 (PIMs) は,高齢者にリスクをもたらします.
- PIMの罹患率を理解することは,患者の安全にとって極めて重要です.
研究 の 目的:
- 家庭医療を受ける介護依存の高齢者の人口統計的特徴を決定する.
- この集団におけるPIM処方と入院または死亡の関連性を評価する.
主な方法:
- 日本 クレ市で高齢者 (≥65歳) の健康保険請求データを遡及的に分析した.
- 人口統計データ,診断,長期ケア (LTC) の必要性,薬剤のプロファイルが含まれています.
- STOPP-J基準で定義されたPIMで,入院と死亡に関連する要因を特定するために,ロジスティック回帰を用いた統計分析.
主要な成果:
- 2052人の参加者 (平均年齢86. 5歳,71. 7%が女性) が含まれた.
- PIMの流行は,より高いLTC需要で増加した (最大26. 0%).
- 薬の量,PIM,そして中等レベルの治療は,入院リスクの増加と関連していました.
結論:
- 潜在的に不適切な薬は 家庭に閉じ込められた高齢者の間で一般的です
- 障害のレベルとポリファーマは 高い入院率と関連しています
- この脆弱な集団では定期的な薬剤検査が推奨されます.
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