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家庭での医療を受ける高齢者に対する不適切な薬剤

Yukari Hattori1, Taro Kojima2, Hironobu Hamaya3

  • 1Department of Geriatric Medicine, The University of Tokyo, Tokyo, Japan.

Annals of geriatric medicine and research
|September 3, 2025
PubMed
まとめ

潜在的に不適切な薬 (PIMs) は,家庭医療を受ける介護に依存した高齢者の間で一般的です. 特に障害のある人にとって 病院入院のリスクを減らすには 薬を慎重に検討することが重要です

キーワード:
家庭介護サービスポリファーマシー潜在的に不適切な薬

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科学分野:

  • ゲロントロジー
  • 薬理学について
  • 公衆衛生

背景:

  • 家庭医療は高齢者にとって不可欠です
  • 潜在的に不適切な薬 (PIMs) は,高齢者にリスクをもたらします.
  • PIMの罹患率を理解することは,患者の安全にとって極めて重要です.

研究 の 目的:

  • 家庭医療を受ける介護依存の高齢者の人口統計的特徴を決定する.
  • この集団におけるPIM処方と入院または死亡の関連性を評価する.

主な方法:

  • 日本 クレ市で高齢者 (≥65歳) の健康保険請求データを遡及的に分析した.
  • 人口統計データ,診断,長期ケア (LTC) の必要性,薬剤のプロファイルが含まれています.
  • STOPP-J基準で定義されたPIMで,入院と死亡に関連する要因を特定するために,ロジスティック回帰を用いた統計分析.

主要な成果:

  • 2052人の参加者 (平均年齢86. 5歳,71. 7%が女性) が含まれた.
  • PIMの流行は,より高いLTC需要で増加した (最大26. 0%).
  • 薬の量,PIM,そして中等レベルの治療は,入院リスクの増加と関連していました.

結論:

  • 潜在的に不適切な薬は 家庭に閉じ込められた高齢者の間で一般的です
  • 障害のレベルとポリファーマは 高い入院率と関連しています
  • この脆弱な集団では定期的な薬剤検査が推奨されます.