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Updated: Sep 9, 2025

Selected Reaction Monitoring Mass Spectrometry for Absolute Protein Quantification
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輝くものはすべて金ではない:タンパク質化学モデルの厳格な評価の重要性

Polina Avdiunina1, Shamieraah Jamal1,2, Filipp Gusev1,2

  • 1Department of Chemistry, Mellon College of Science, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.

Journal of chemical information and modeling
|September 3, 2025
PubMed
まとめ

薬剤発見のためのタンパク質化学モデル (PCM) は厳格な評価を必要としています. データの分割とクラス不均衡はモデルの性能に重大な影響を及ぼし,機械学習/ディープラーニング-PCMの汎用性の課題を強調しています.

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Drug disposition in the body is a complex process and can be studied using two major approaches: the model and the model-independent approaches.
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