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Updated: Sep 9, 2025

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
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進行した固体腫瘍におけるドルヴァルマブとの併用療法として,抗CD39モノクローン抗体であるIPH5201

John Powderly1, Martina Imbimbo2, Antoine Italiano3

  • 1Carolina BioOncology Institute, Huntersville, NC, United States.

Cancer research communications
|September 3, 2025
PubMed
まとめ

IPH5201は,分化39 (CD39) 阻害剤のクラスターであり,進行した固体腫瘍の患者で良好に耐えた. 薬剤は薬理学的に有効な用量を示し,腫瘍CD39の活性を低下させ,疾患の安定化の可能性を示した.

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