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Updated: Sep 9, 2025

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ガン治療のための免疫療法を開発するために,シグレク媒介の相互作用を妨害する

Heinz Läubli1,2, Ajit Varki2,3

  • 1Laboratory for Cancer Immunotherapy, Department of Biomedicine, University of Basel, Switzerland, and Division of Oncology, University Hospital Basel, Switzerland.

Expert opinion on therapeutic targets
|September 3, 2025
PubMed
まとめ

シアリック酸を結合する免疫グロブリン型レクチン (Siglec) の相互作用をターゲットにすることで,がんの免疫療法抵抗を克服することができます. これらの経路を阻害することで 抗腫瘍免疫を高め 早期臨床試験で患者の治療結果を改善することが期待されています

キーワード:
ガンに対する免疫療法抗体療法グライコ免疫チェックポイントレクチンシアリック酸シアリダゼ

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