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Updated: Sep 9, 2025

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
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Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis

Published on: September 30, 2017

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生ワクチン株のフランシセラ・トゥラーネシスの酸化ストレス反応におけるチオレドキシン還元酵素 (TrxB) の役割

Matthew Higgs1, Zhuo Ma1, Anthony Centone2

  • 1Department of Life Sciences, Albany College of Pharmacy and Health Sciences, Albany, New York, USA.

Journal of bacteriology
|September 3, 2025
PubMed
まとめ

チオレドキシン還元酵素遺伝子 (trxB) は,Francisella tularensisが酸化ストレスとマクロファージの中で生き残るために不可欠です. しかし,TrxBはオーラノフィンの標的ではありません.

キーワード:
フランセッラ抗生物質に対する耐性アウラノフィンマクロファージ内生存率酸化ストレスチオレドキシン還元酵素

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