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Updated: May 4, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
08:29

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

Published on: February 1, 2019

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最適なバランスのとれたイオン化/カチオン性脂質含有量を持つペギュレートされた固体脂質ナノ粒子による強化されたmRNAとpDNAの配送

Nipuni Maniyamgama1,2, Ki Hyun Bae1, Jialing Lee1

  • 1Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, Centros #06-01, Singapore 138668, Republic of Singapore. yyyang@bti.a-star.edu.sg.

Journal of materials chemistry. B
|September 3, 2025
PubMed
まとめ

研究者は,遺伝子配送の強化のために,新しいイオン化可能な脂質組み合わされたPEG-iSLNsを開発しました. これらのPEG-iSLNは優れたmRNAトランスフェクションと安定性を示し,in vivoのアプリケーションに希望を示しています.

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