ADHDの子どもにおける微量栄養素の持続効果:ランダム化対照試験
Adarsh Chand1, Kathryn Darling1, Julia J Rucklidge2
1School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand.
European child & adolescent psychiatry
|September 3, 2025
まとめ
注意欠陥/多動性障害 (ADHD) に対する微量栄養素治療は20週間にわたって持続的な改善を示しました. プラセボを投与した子供たちは,マイクロ栄養素を投与した後に,継続的な治療を受けた子供達と同程度に改善しました.
科学分野:
- 栄養精神科
- 小児神経学
背景:
- 注意欠陥/多動性障害 (ADHD) は一般的な神経発達障害である.
- 微量栄養素のサプリメントはADHDの症状の管理に 有望であることが示されています
研究 の 目的:
- ADHDに対する 微量栄養素の長期的有効性を調べるため
- 微量栄養素の治療期間の影響を評価する
- 最初,プラセボにランダムに割り当てられた子供に対する効果を評価する.
主な方法:
- 10週間のランダム化対照試験 (RCT) に続いて10週間のオープンラベル (OL) 段階.
- 参加者 (7〜12歳) はRCT段階で微量栄養素またはプラセボを受け,その後はOL段階で微量栄養素を受けました.
- 評価にはADHDの症状,感情的不調,および臨床的全体的な印象改善 (CGI-I) が含まれていた.
主要な成果:
- 最初プラセボを受けた子どもは,微量栄養素への移行後 (32. 4%から64. 9%) 症状の有意な改善を示しました.
- 20週間にわたって微量栄養素を摂取した子どもは,高い反応率 (46. 3%から63. 4%) を維持した.
- すべての子供の半分以上がOL段階の終わりまでに反応を示し,グループ間の有意な差異や副作用の増加はなかった.
結論:
- 微量栄養素はADHDの有効な治療法であり 症状のコントロールを維持し改善します
- 治療期間を延長することで,プラセボに反応した患者は継続治療群に追いつくことができる.
- ADHDの微量栄養素補充は安全で有効で 症状の改善と身体の成長を促進します
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