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Updated: Sep 9, 2025

Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model
08:43

Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model

Published on: February 7, 2018

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Komagataella phaffiiのトリプルヘリクル構造のタイプIII再結合ヒトコラーゲンの効率的な分泌表現

Yaqian Ma1,2, Yang Li3, Nan Wang1,2

  • 1Department of Biological Engineering, College of Life Sciences, Yantai University, Yantai, 264005, China.

Applied microbiology and biotechnology
|September 3, 2025
PubMed
まとめ

酵母から 安定したトリプルヘリクリン 再結合ヒトコラーゲン (rhCol) を 生成する 新しい方法を開発しました このスケーラブルなプラットフォームは 高い生産性を実現し 機能的なコラーゲンの 工業的および臨床的応用への道を開きます

キーワード:
コマガテラファフィープロリル-4-ヒドロキシラーゼタンパク質発現リコンビネントヒトコラーゲントリプルヘリックス

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Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

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High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension11:42

High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension

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Type IV Collagen of Basal Lamina

Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen  forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
A type IV collagen molecule has six alpha chains which can...
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Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
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Collagens are the Major Structural Proteins of ECM

Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
Connective tissue proper includes loose...
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