Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

206
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
206
Digestive Functions of the Large Intestine01:20

Digestive Functions of the Large Intestine

704
The large intestine is where the final stages of digestion happen. When the cecum receives chyme, it contains undigested carbohydrates that undergo fermentation. Gut bacteria ferment these carbohydrates to produce short-chain fatty acids that provide some energy and help synthesize essential vitamins.
As the chyme moves to the colon, it triggers two characteristic sluggish contractions - haustral churning and mass peristalsis. Haustral churning involves the rhythmic contraction and relaxation...
704
Histology of the Large Intestine01:26

Histology of the Large Intestine

1.6K
The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
1.6K
Large Intestine01:09

Large Intestine

1.9K
The large intestine is divided into three main regions: the cecum, colon, and rectum. Extending from the ileocecal valve to the anus, it frames the small intestine on three sides.
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
1.9K
Fascicle Arrangement in Skeletal Muscles01:25

Fascicle Arrangement in Skeletal Muscles

2.4K
Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
The four primary types of muscle based on fascicle arrangement are:
2.4K
Anatomy of the Intestines01:23

Anatomy of the Intestines

73.8K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
73.8K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Identifying targeting signals and distinct localization-based roles of yeast aldehyde dehydrogenase Hfd1.

The FEBS journal·2026
Same author

Midgut protrusion, rotation, and retraction induced by temporal alteration in differential growth.

Biomechanics and modeling in mechanobiology·2025
Same author

In vitro functional reconstitution of cofactor-dependent plant cytochrome P450 system on artificial liposomes.

Bioscience, biotechnology, and biochemistry·2025
Same author

Oligomer-based functions of mitochondrial porin.

Nature communications·2025
Same author

Effect of menstrual cycle and menopause on human gastric electrophysiology.

American journal of physiology. Gastrointestinal and liver physiology·2024
Same author

Author Correction: A multipoint guidance mechanism for β-barrel folding on the SAM complex.

Nature structural & molecular biology·2023

関連する実験動画

Updated: Sep 9, 2025

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

21.5K

周回収縮による腸内浸出

Hitomi Okino1, Hironori Takeda2,3, Shunichi Ishida1

  • 1Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe, 657-8501, Japan.

Biomechanics and modeling in mechanobiology
|September 3, 2025
PubMed
まとめ

小腸の筋肉の動きが調整されないと 小腸の動きが調整されないと 小腸の動きが調整されないと 小腸の動きが調整されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと 小腸の動きが制御されないと この研究では 腸の仕組みをモデル化して 筋肉の調整不良が この危険な状態に 繋がる様子を明らかにしました

キーワード:
バックリング変形連続力学インタススセプション筋肉の収縮とリラックス

さらに関連する動画

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
09:24

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Published on: February 11, 2021

7.2K
Creation of Abdominal Adhesions in Mice
06:44

Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

12.8K

関連する実験動画

Last Updated: Sep 9, 2025

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

21.5K
Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
09:24

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Published on: February 11, 2021

7.2K
Creation of Abdominal Adhesions in Mice
06:44

Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

12.8K

科学分野:

  • 胃腸内科
  • コンピュータ生物学
  • 小児外科

背景:

  • 小児性腸内閉塞は通常,大腸内閉塞の侵入を含む大腸内閉塞領域に影響する.
  • 以前の研究では,腸内受容,炎症,腸の運動性との関連が示唆されていましたが,その正確なメカニズムは完全に理解されていません.

研究 の 目的:

  • 乳児内静止症のメカニカルな基礎を調査する. 乳児内静止症中の滑らかな筋肉の活動が重要な要因であると仮定する.
  • 腸内メカニズムをシミュレートし,陰道化につながる条件を特定するために,計算モデルを開発し,利用する.

主な方法:

  • 端のイレウムをハイパー弾性チューブとして表現する計算モデルを開発した.
  • 滑らかな筋肉の収縮と放松をシミュレートし,円形と縦方向の筋肉の相互作用に焦点を当てます.
  • 腸壁の調整された筋肉活動と非調整された筋肉活動の 機械的結果を分析した.

主要な成果:

  • 模型の管壁の縦断的なリラックスと組み合わせた周囲の収縮が陰道化を引き起こすことが示された.
  • 収縮の局所的で正方形の領域が 超弾性管に現れるときに 収縮が起こることが観察されました
  • 円状と縦状の滑らかな筋肉の 協調不良が 腸内壁の 侵入の有効なメカニズムであることを確認しました

結論:

  • 腸内の滑らかな筋肉のダイナミクスは,小児の腸内静脈形成を引き起こします.
  • 特に局所的または非協調的な収縮は,小児性腸内受容症を発症するリスクの予測指標として機能する.