進行中のHER2陰性乳がん患者におけるナブパクリタキセルの利用,有効性,安全性,および生活の質を評価するSERAPHINA研究に関するコメント

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...