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Updated: Sep 9, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
12:40

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

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新しいザヌブルチニブ160mg錠剤を評価するための相対的生物利用性,食品効果,および生物同等性研究:健康なボランティアの2つの第1相試験の結果

Bilal Tariq1, Chester Lin2, Vaibhav Mundra1

  • 1Clinical Pharmacology & Pharmacometrics, BeOne Medicines Ltd, San Carlos, CA, USA.

Clinical pharmacology in drug development
|September 3, 2025
PubMed
まとめ

新しいザヌブルチニブ錠剤はカプセルと同等で,全身の曝露も同等です. この新しい錠剤は,食事と併用しても服用でき,錠剤の負荷を減らすことで患者さんの服用習慣を改善する可能性があります.

キーワード:
BTK 阻害剤バイオエキワレンス臨床薬理学食品効果薬理学

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