Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

5.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.1K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

3.1K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.1K
The Thyroid Gland01:23

The Thyroid Gland

4.3K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.3K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.2K
Depression: Overview01:18

Depression: Overview

331
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
331
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.9K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.9K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

The SINTER study: a recall-by-genotype design with multidimensional musculoskeletal phenotyping across internal-medicine outpatient clinics.

European journal of epidemiology·2026
Same author

Advancements and Insights in Thyroid Health.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same author

Barriers for Secondary Hypertension Screening in the United States: A National Physician Survey.

Journal of the American Heart Association·2026
Same author

Determinants of pro- and anti-inflammatory cytokine profiles across populations.

BMC medicine·2026
Same author

Determinants of Immunoglobulin-G N-Glycan Patterns in the Aging General Population.

Allergy·2026
Same author

Natural history of thyroid function in ageing: an individual participant data analysis of 137 488 participants from 31 prospective cohort studies.

The lancet. Diabetes & endocrinology·2026
Same journal

WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

JAMA·2026
Same journal

FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

JAMA·2026
Same journal

HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

JAMA·2026
Same journal

US Dietary Supplement Use Increasing, Especially in Older Adults.

JAMA·2026
Same journal

Heat Stress From Climate Change Surges Globally.

JAMA·2026
Same journal

Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

JAMA·2026
関連記事をすべて見る

関連する実験動画

Updated: Sep 9, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.8K

甲状腺 機能 低下: 概要

Layal Chaker1,2,3, Maria Papaleontiou4,5

  • 1Academic Centre for Thyroid Disease, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands.

JAMA
|September 3, 2025
PubMed
まとめ
この要約は機械生成です。

甲状腺ホルモンの欠乏症である 甲状腺機能低下症は 世界中で何百万人もの人に 影響しています 早期診断とレボチロキシン治療は 症状の管理と心臓機能不全のような重篤な合併症の予防に不可欠です

さらに関連する動画

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.0K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

730

関連する実験動画

Last Updated: Sep 9, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.8K
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.0K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

730

科学分野:

  • 内分泌学
  • 内科 医学

背景:

  • 甲状腺機能低下症は,甲状腺ホルモンの生産が不十分であることが特徴である一般的な内分泌疾患です.
  • ヨウ素の摂取などの要因によって 世界中で流行が異なっており 女性や高齢者に不釣り合いな影響を及ぼします
  • 治療されていない甲状腺機能低下は 心不全やミクセデマ・コマなど 深刻な健康問題を引き起こす可能性があります

研究 の 目的:

  • 甲状腺機能低下症 の 原因,症状,診断,治療 に 関する 総合 的 な 概要 を 提供 する.
  • 早期診断と適切な管理の重要性を強調し,健康上のリスクを軽減する.

主な方法:

  • 甲状腺機能低下に関する最新の医学文献のレビュー
  • 罹患率,危険因子,臨床症状,診断基準,治療ガイドラインの分析

主要な成果:

  • ハシモト甲状腺炎はヨウ素が充足した地域では 主要な甲状腺機能低下の原因である.
  • 一般的な症状には 疲労,体重増加,認知障害,月経不定期などがあります.
  • 生化学的診断は,チロトロピン (TSH) の上昇と,フリーチロキシン (T4) の低下に依存する.

結論:

  • 甲状腺機能低下症には様々な症状があり 心血管や生殖に関する重大な合併症を引き起こす可能性があります
  • レボチロキシンは標準的な第一線治療法であり,個別の投与と定期的なモニタリングが必要です.
  • 効果的な治療は,TSHのレベルを正常化し,症状を緩和し,深刻な長期的な健康被害を防ぐことができます.