プエルトリコの環境有害物質への潜在的曝露と癌のリスクの増加
Nancy Raquel Cardona-Cordero1, Ana Patricia Ortiz1, Lenulisy Rosado-Estrada2
1University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, United States.
まとめ
プエルトリコでは有毒な環境汚染物質が 癌のリスク増加に繋がっています 工業的に有毒な化学物質が放出されている地域の住民は,特に高度に汚染された地域の男性では,全体的に高い癌率を示しました.
科学分野:
- 環境 健康
- 流行病学について
- 毒理学について
背景:
- 毒性のある環境汚染物質は 様々な癌の危険因子として認識されています
- このような汚染物質に15年間曝露した後のプエルトリコの癌リスクを評価するために,生態学的な研究が計画された.
研究 の 目的:
- プエルトリコにおける産業用有毒化学物質の排出と癌発生の関連性を評価する.
- 毒性化学物質への曝露のレベルが異なる自治体における癌リスクの定量化
主な方法:
- プエルトリコ (2018-2022) のがん発生データと環境保護庁の毒性放出量 (TRI) (2006-2020) を利用した.
- 工業施設で発生する有毒化学物質の排出量を報告した汚染地域を定義する.
- SEER*Statを用いて,がんの種類,性別,TRIの発生頻度によって年齢標準化された相対リスク (RR) と95%信頼区間を計算した.
主要な成果:
- 2018年から2022年の間に合計80,179件の侵襲性がんが診断されました.
- 汚染された自治体の住民は,すべてのタイプの癌のリスクが7%高かった (RR: 1.07).
- 高度汚染地域に住む男性ではがんのリスクが12%増加 (RR: 1.12),女性では5%増加 (RR: 1.05).
結論:
- TRIを報告する産業施設を持つプエルトリコの自治体では,がんの発生率が高いことが示唆されています.
- 毒性化学物質への曝露を減らすための環境介入と公衆衛生戦略の必要性を強調する.
- プエルトリコの癌の負担と 産業の有毒排出量との関連を 理解するのに貢献します
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