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Updated: Sep 9, 2025

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イリノテカンの注射反応と重度の毒性の関連性

Kelly I Nugent1, Lyucheng Huang, Maisa Nazzal

  • 1Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan, USA.

Pharmacogenetics and genomics
|September 3, 2025
PubMed
まとめ

CES1 と ABCG2 の遺伝的変異は,中性不全を含む重度のイリノテカンの毒性のリスクを増加させる可能性があります. イリノテカンの投与における潜在的な臨床応用のために,これらの発見を確認するためにさらなる研究が必要である.

キーワード:
急性コレリン症候群インフィュージョンイリノテカン薬剤遺伝学

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