ヨーロッパにおける処方オピオイド使用の動向: 7カ国を含むDARWIN EU®多国籍コホート研究
Junqing Xie1, Mike Du1, Yuchen Guo1
1Pharmaco- and Device Epidemiology Group, Centre of Statistics in Medicine, NDORMS, University of Oxford, England, United Kingdom.
Frontiers in pharmacology
|September 3, 2025
まとめ
オピオイドの処方頻度は一部のヨーロッパ諸国では減少したが,全体的なオピオイド使用率は安定したままである. 継続的なモニタリングは,特にパンデミック後の時代において,変化する傾向を理解するために極めて重要です.
科学分野:
- 公衆衛生
- 流行病学
- 薬理学について
背景:
- オピオイド危機は 世界的に大きな公衆衛生問題となっています
- ヨーロッパにおけるオピオイド危機の可能性が懸念されています.
- この研究は,ヨーロッパのオピオイド使用パターンの理解の必要性に対応しています.
研究 の 目的:
- 7つのヨーロッパ諸国におけるオピオイド使用の傾向を評価する.
- 新規オピオイド使用者の処方薬の特徴について
- ヨーロッパにおけるオピオイド使用管理のための公衆衛生戦略を策定する.
主な方法:
- 電子医療記録を用いた多国籍コホート研究
- 初等医療,専門医療,病院でのデータを分析した.
- オピオイド処方の流行と発生率は,OMOP共通データモデルを使用して推定されました.
主要な成果:
- オピオイドの処方頻度は,一部のプライマリケア施設では減少したが,他の施設では増加した.
- オキシコドン,モルヒン,フェンタニルなどの特定のオピオイドの流行が増加しました.
- 新しいオピオイドの処方箋の主な症状は呼吸器系と痛みでした.
結論:
- いくつかの地域では新しいオピオイドの処方箋が減少したにもかかわらず,全体的な流行率は安定したままでした.
- オピオイドの処方パターンの進化を追跡するには,さらなるデータ収集が不可欠です.
- パンデミック後の監視は特に重要です.
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