関連する実験動画

Updated: May 3, 2026

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS
11:00

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS

Published on: May 20, 2013

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小児科におけるセルメチニブの治療薬モニタリング:LC-MS/MSとLC-HRMSの組み合わせによるアプローチ

Alessia Cafaro1, Andrea Santangelo2,3, Sebastiano Barco1

  • 1Biochemistry, Pharmacology and Newborn Screening Unit, Central Laboratory of Analysis, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Frontiers in pharmacology
|September 3, 2025
PubMed
まとめ

新しい方法は,NF1患者のセルメチニブを正確に測定し,薬物の代謝の変化を明らかにします. これは,プレキシ型神経線維腫の個別化投与をサポートし,神経線維腫1型の治療を改善します.

キーワード:
LC-MS/MS についてメタボライト神経線維腫1型セルメチニブ治療薬モニタリング

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