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Updated: Sep 9, 2025

Working with Auditory HEI-OC1 Cells
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オメプラゾルのHK-2細胞におけるバンコミシン細胞毒性およびネズミにおける腎臓損傷に対する保護効果

Jiaxu Wu1, Xikun Wu1, Wenli Li1

  • 1Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

BioMed research international
|September 3, 2025
PubMed
まとめ

細胞内バンコミシン蓄積は腎臓の損傷を引き起こす. オメプラゾールは,P-グリコタンパク質と有機カチオントランスポーター-2の調節によってバンコミシン濃度を低下させ,腎臓を保護する.

キーワード:
HK-2 セル細胞内濃度オメプラゾールネズミバンコミシン

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