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Updated: Sep 9, 2025

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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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1990年から2021年までの脳卒中による世界的な負担と傾向
Zi-Han Yin1,2, Qiong-Nan Bao1,2, Jiao Chen1,2
1School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Clinical kidney journal
|September 3, 2025
まとめ
腎臓機能障害 (KD) は脳卒中のリスクを大幅に増加させる. KDに関連した世界的な脳卒中の負担は1990年から2021年にかけて大幅に増加し,成長すると予測されており,ターゲット化された公衆衛生の介入が必要である.
科学分野:
- 腎臓科
- 神経科学
- 公衆衛生
- 流行病学
背景:
- 腎機能障害 (KD) は,脳卒中とそのサブタイプ (SSS) の確立された危険因子です.
- KDによるSSSの総合的な負担の評価は欠けている.
- この研究は,KDに関連するSSSの動向の詳細な分析の必要性を扱っています.
研究 の 目的:
- 1990年から2021年までのKD関連のSSSの長期的な動向を比較する.
- 2045年まで KDに関連するSSSの将来の病気負担を予測する.
- 人口統計と地域による KD 関連 SSS 負担の変動を分析する.
主な方法:
- 2021年世界疾病負担調査 (GBD) のデータを活用した.
- KDに関連するSSSの推定死亡率と障害調整寿命 (DALYs)
- 年齢標準化率および性別,年齢,SDI,地域,国別層別分析の推定年率 (EAPC) を計算した.
主要な成果:
- 1990年から2021年の間に,KDに関連した脳卒中の死亡率は40.4%増加し,DALYは36.7%増加しました.
- 血性脳卒中と脳内出血の負担は,EAPCの変動で増加しました.
- 人口増加と高齢化が増加に寄与している中部SDI地域と東アジアで,最も高い負担が観察されました.
結論:
- 長期的傾向がわずかに低下しているにもかかわらず,KD関連のSSSの総負荷は著しく増加しています.
- 地域,国,性別,年齢層によって顕著な差異がある.
- KDに関連するSSSの増大する課題は,特定の治療戦略と公衆衛生のイニシアチブを必要とします.
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