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Updated: Sep 9, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

Published on: September 15, 2018

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家族性高コレステロール血症の中国人患者におけるタフォレシマブの有効性と安全性: ランダム化制御試験の体系的レビューとメタ解析

Alaa Ramadan1, Ravindra Reddy Gangavarapu2, Hina Aziz3

  • 1Faculty of Medicine, South Valley University, Qena, Egypt.

Annals of medicine and surgery (2012)
|September 3, 2025
PubMed
まとめ

タフォレシマブは,家族性高コレステロール血症 (FH) の中国人患者において,LDL- Cおよびその他の脂質のレベルを著しく低下させる. 副作用はより一般的であったが,重篤な症状はプラセボと違わず,心血管リスクの減少の可能性を示した.

キーワード:
中国人患者PCSK9阻害剤家族性高コレステロール症 (FH)低密度の脂質タンパク質コレステロール (LDL-C)タフォレシマブ

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