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Updated: Sep 9, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

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レミフェンタニル誘発の術後の過敏症のメカニズム: 総合的なレビュー

Kexin Zhu1,2, Xiaolin Wen1,2, Xuan Mei1,2

  • 1School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, People's Republic of China.

Drug design, development and therapy
|September 3, 2025
PubMed
まとめ

レミフェンタニル誘発性過敏症 (RIH) は,麻酔を中止した後の痛みの過敏症である. 複雑な分子の仕組みを理解することは 手術後の痛み管理の改善の鍵です

キーワード:
NLRP3炎症ゾームNMDA受容体について中央の感受性膠質細胞の活性化術後の過敏症レミフェンタニル

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
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