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Updated: Sep 9, 2025

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

Published on: May 27, 2011

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免疫の逆進化:不死のB細胞のクローンは,ウイルスの脱出に対抗するために,ex vivoの指向的な進化を経験することができる

Casper Marsman1, Jurgen Heinen1, Vanessa Clerico Mosina1

  • 1Kling Biotherapeutics, Amsterdam, Netherlands.

Frontiers in immunology
|September 3, 2025
PubMed
まとめ

この研究は,不死のB細胞ライブラリを開発し,JN.1のような免疫脱出株を含む,進化するSARS-CoV-2変種に対して有効な抗体を生成するために進化を導いた.

キーワード:
アフィニティの成熟抗体発見バイパラトピー抗体誘導された進化人間のB細胞

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