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Updated: Sep 9, 2025

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
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高リスクの急性骨髄性白血病または骨髄不全症候群の患者の再発予防のために,ルクソリチニブとデシタビンと,ブスルファン- サイクロフォスファミドのコンディショニング療法

Yujun Wei1,2, Songhua Luan3, Lu Wang2

  • 1School of Medicine, Nankai University, Tianjin, China.

Frontiers in immunology
|September 3, 2025
PubMed
まとめ

この研究では,改変されたブスルファン- サイクロフォスファミド (Rux- Dec- mBu/ Cy) によるルクソリチニブとデシタビン療法は,高リスクの急性骨髄性白血病 (AML) または骨髄分裂症候群 (MDS) の患者の再発を低減するのに安全で有効であることが示されています. 2年間の再発率は19. 0%でした.

キーワード:
急性骨髄性白血病アロゲン性造血幹細胞移植コンディショニング骨髄不形成症候群再発する

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