1990年から2021年までの先天性心疾患の世界的,地域的,国家的な負担と2050年までの予測

Erdengqieqieke Ye¹, Erman Wu^2,3, Tong Tang³

¹Department of Prenatal Diagnosis, Reproductive Medicine Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Frontiers in pediatrics

|September 3, 2025

まとめ

生まれながらの心異常は世界中で子供に影響を与えます死亡率は減少しているが,特に若年層では増加しており,公平性を目指した公衆衛生戦略が必要である.

科学分野:

心臓病科
公衆衛生
世界保健疫学

背景:

生まれながらの心異常 (CHA) は,世界中で最も一般的な出生障害を表しています.
CHAは小児の集団と世界の保健医療システムに大きな影響を及ぼします.
世界的な傾向を理解することは公衆衛生の介入に不可欠です

研究の目的:

1990年から2021年にかけてのCHAの世界的負担を分析する.
社会人口指数 (SDI) のクインティルの間で性層化傾向を調査する.
CHAの流行と死亡率の将来の傾向を予測する.

主な方法:

グローバル・バード・オブ・ディジーズ (GBD) 研究データを活用した.
性別別別別評価指標:流行,発生率,死亡率,DALY,YLL,YLD
21のGBD地域と204カ国のデータを分析した.

主要な成果:

CHAの流行と発生率は安定しており,SDIの低い地域では発生率が高かった.
死亡率,DALYs,YLLsは世界的に減少し,特にSDIが低い地域では男性の割合が高くなりました.
障害者の負担が増加していることを示し,2050年までに増加すると予測されています.

結論:

CHAの負担は性別とSDIによって影響され,罹患率が上昇し,死亡率が低下しています.
YLDの増加は,ターゲット化された公衆衛生戦略の必要性を強調しています.
障害者負担の増大に対処することはグローバルな健康の公平性にとって不可欠です

キーワード:

心臓の先天性異常障害調整寿命年数世界的な病気の負担性別分別分析社会人口指数障害で過ごした年数

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