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Updated: Sep 9, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

Published on: August 2, 2018

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VIPR1はクプロプトーシスを誘発し,大腸がんにおけるHIF-1α経路を阻害する

Xue Liu1, Ye Lin1, Jingzhi Zhang1

  • 1Department of Gastroenterology, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou City, Jiangxi Province, China.

Journal of biochemical and molecular toxicology
|September 3, 2025
PubMed
まとめ

プログラムされた細胞死経路であるクプロプトーシスは 結腸がんの腫瘍抑制剤として作用します VIPR1遺伝子の過剰発現は,HIF-1αシグナル伝達を低下させることで,癌細胞の成長と移動を阻害し,クプロプトーシスを促進する.

キーワード:
HIF-1α経路についてVIPR1 についてバイオマーカー大腸がんカプロプトーシス

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