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Updated: Sep 9, 2025

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

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ミトコンドリア膜ポテンシャルを調節することによって,TPC-1の甲状腺がん細胞における癌の特徴を標的とするCAPEの治療的可能性

Yasin Tülüce1, Hümeyra Bucak2, Sedat Köstekci3

  • 1Department of Medical Biology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Türkiye.

Journal of biochemical and molecular toxicology
|September 3, 2025
PubMed
まとめ

カフェイン酸フェネチルエステル (CAPE) は,ミトコンドリア経路をターゲットにすることで,ヒトのTPC-1型甲状腺がん細胞におけるアポトーシスを効果的に誘導する. この天然化合物は 細胞の移動とコロニーの形成を阻害することで 将来の癌治療に 期待されています

キーワード:
ATP合成酵素CAPE についてDNA 損傷MMPROMO1 についてアンチメスタシスアポトーシス細胞毒性甲状腺がん

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Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines07:49

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