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Updated: Sep 9, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

174

デュロキセチンとフルオキセチンの有効性を高めるためのビタミンDの役割の研究:NRF2活性化,酸化ストレス,神経化学的調節に関するメカニズム的洞察

Naveed Khan1, Shakir Ullah1,2, Muhammad Ilyas2

  • 1Institute of Pharmaceutical Sciences, Khyber Medical University, Peshawar, Pakistan.

Journal of biochemical and molecular toxicology
|September 3, 2025
PubMed
まとめ

ビタミンDは,抗酸化酵素とNrf2発現を刺激することで,ネズミのうつ病モデルで抗うつ効果を示しています. このビタミンは セロトニンとノレピネフリンのレベルを高め 鬱病の治療策となる可能性があります

キーワード:
Nrf2 についてカタラゼコルチゾールうつ病酵素抗酸化システムグルタチオンマロンディアルヘイドスーパーオキシードジスミュータゼ

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