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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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ファルカリンジオールは,JAK/ STAT3軸の調節により,悪性がんの進行を抑制し,非小細胞肺がんにおけるフェロプトーシスを誘発する

Zhenliang Shi1, Yimeng Shen1, Xin Liu1

  • 1Department of Thoracic Surgery, Chest Hospital, Tianjin University, Tianjin, China.

Journal of biochemical and molecular toxicology
|September 3, 2025
PubMed
まとめ

ファルカリンジオール (FAD) は,フェロプトーシスを誘発し,JAK/ STAT3経路を阻害することによって,非小細胞肺がん (NSCLC) の成長と拡散を抑制する. この化合物は,正常な細胞に対する有意な毒性なしにNSCLCの治療に希望を示しています.

キーワード:
JAK/STAT3 についてNSCLC についてファルカリンジオールフェロプトーシス侵入する

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