関連する実験動画

Updated: Sep 9, 2025

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
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Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

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膀を用いて膜タンパク質の原生構造を捕捉する

Hang Liu1, Chun Mong Tse1, Shangyu Dang1,2

  • 1Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Proceedings of the National Academy of Sciences of the United States of America
|September 3, 2025
PubMed
まとめ

この研究は,膜タンパク質の構造研究のための新しい膀ベースの方法を導入し,ネイティブの脂質環境を保存し,洗剤のスクリーニングを排除します. このアプローチにより,ACRBのような重要なタンパク質の 高解像度の冷凍-EM構造が得られました.

キーワード:
クリオ・エムin situ 構造生物学膜タンパク質膜膀ミトコンドリア膜小胞

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