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Updated: Sep 9, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

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SCAPは,IκBαの安定性とユビキチネーションを調節することによって,Trim27と相互作用して,血管新生性増殖を促進する

Yingcheng Yao1, Xing Wang1, Chengcheng Xuan1

  • 1Centre for Lipid Research & Chongqing Key Laboratory of Metabolism on Lipid and Glucose, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Aging and disease
|September 3, 2025
PubMed
まとめ

ステロール調節要素結合タンパク質分裂活性化タンパク質 (SCAP) は,血管の滑らかな筋肉細胞の増殖と移動を促進し,ネオインティマル・ハイパープラジアを誘発する. SCAP/IκBα/NF-κB経路をターゲットにすることで,年齢に関連する血管疾患を予防することができます.

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