レドックス反応性Cabazitaxel-Zosuquidar結合体とDSPE-PEG2kから自己組み立てられたナノドラッグは,非小細胞肺がんにおける多剤耐性を逆転させる

Yingchun Liu1, Penghui Wang1, Wenhui Gao1

  • 1School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.

ACS applied bio materials
|September 3, 2025
PubMed
まとめ

この研究では,薬剤耐性非小細胞肺がん (NSCLC) の治療のために,化学療法薬と耐性阻害剤を組み合わせたスマートなナノ粒子が開発されました. これらのナノ粒子は 毒性が最小限に抑えられ 腫瘍の成長を抑制します

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