乳がんの進行段階で診断される社会的決定因子

Madonna A Fekry^1,2, Loay Kassem^3,4, Justin C Yang^2,5,6

¹Clinical Research Department, Cairo Oncology Center, Cairo, Egypt.

JCO global oncology

|September 3, 2025

まとめ

エジプトの乳がん患者は進行した病気を患っていることが多いのです失業と農村部での生活は診断の遅い段階に関連した重要な要因であり,公衆の意識と早期発見のイニシアチブの必要性を強調しています.

科学分野:

腫瘍学
公衆衛生
流行病学

背景:

乳がん (BC) はエジプトで進行段階で診断されることが多い.
遅延の原因を理解することは患者の治療結果を改善するために極めて重要です

研究の目的:

エジプトの患者で進行段階の乳がんに伴う社会統計学的および臨床的要因を調査する.
ターゲットを絞った介入のための遅い診断の主要な予測要因を特定する.

主な方法:

レトロスペクティブコホート研究では,2011年から2020年の間に診断されたエジプトの乳がん患者1,953人のデータを分析した.
ロジスティック回帰モデルを使用して,患者の特徴と進行したBCの関連性を評価した.

主要な成果:

患者の43%以上が進行した乳がんと診断されました.
多変量分析では,失業率 (aOR,1.44) と農村居住率 (aOR,1.88) が,先進的なBCに関連する重要な要因として特定されました.
高いKi67% (aOR,1. 01) も,進行した疾患の発現と関連していた.

結論:

失業と農村部での生活はエジプトの進行性乳がんの診断と強く関連しています
乳がんの早期発見を促進するために,公衆の意識を高めるキャンペーンは不可欠です.
脆弱な集団に対する標的型スクリーニングと支援プログラムは早期診断率を向上させる可能性があります

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